The Dresden native moved to Leipzig in summer 2017 to join the RBL academy and was part of the first-team squad for the 2022/23 season. The 19-year-old was included in ten matchday squads this season, but did not feature.
Nickisch made 20 appearances for the RBL U-19s this season, including two games in the UEFA Youth League. He made his debut for the Germany U-19s on May 10, 2023 in a 0-0 draw against Denmark U-19s.